effects of vitamin e on ovarian tissue of rats following treatment with p-nonylphenol: a stereological study

نویسندگان

malek soleimani mehranjani

ali noorafshan

ahmad hamta

hamid reza momeni

چکیده

background: para-nonylphenol (p-np) is one of the environmental pollutants which cause reproductive system disorders. objective: the effects of vitamin e on ovary structure during its development in rats treated with p-np. materials and methods: 32 wistar female rats after mating were divided into 4 groups; control vitamin e (100mg/kg/day) p-np (250mg/kg/day) and p-np + vitamin e. the rats were treated from the day 7 of pregnancy till 21st day of postnatal through sucking period. after weaning the female pups were treated by gavages for 120 days. the total volume of ovary number of follicles volume of oocyte follicular cells and their nuclei and the thickness of zona pellucida were estimated stereologically. the results were analyzed using one way anova and p

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Stereological study of the effects of vitamin E on testis structure in rats treated with para-nonylphenol.

This study was organized to see whether vitamin E, as a strong antioxidant, could affect the abnormalities of testis structure caused by para-nonylphenol (p-NP) during its development. A total of 32 female Wistar rats after mating were divided into four groups (n = 8): control, vitamin E (100 mg kg(-1) per day), p-NP (250 mg kg(-1) per day) and p-NP + vitamin E. The rats were treated from the s...

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عنوان ژورنال:
international journal of reproductive biomedicine

جلد ۸، شماره ۱، صفحات ۱-۰

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